The Biology of Progesterone Receptor in the Normal Mammary gland and in Breast Cancer

Por Obr, Alison, Edwards, Dean P.
Publicado em 2011

Finally! A Model for Progesterone Receptor Action in Normal Human Breast

Por Lydon, John P., Edwards, Dean P.
Publicado em 2009

Minireview: Dynamic Structures of Nuclear Hormone Receptors: New Promises and Challenges

Por Simons, S. Stoney, Edwards, Dean P., Kumar, Raj
Publicado em 2014

Human Progesterone Receptor Displays Cell Cycle-Dependent Changes in Transcriptional Activity

Por Narayanan, Ramesh, Edwards, Dean P., Weigel, Nancy L.
Publicado em 2005

CYCLIN A2 AND ITS ASSOCIATED KINASE ACTIVITY ARE REQUIRED FOR OPTIMAL INDUCTION OF PROGESTERONE RECEPTOR TARGET GENES IN BREAST CANCER CELLS

Por Moore, Nicole L., Edwards, Dean P., Weigel, Nancy L.
Publicado em 2014

The Requirement for p42/p44 MAPK Activity in Progesterone Receptor-Mediated Gene Regulation is Target Gene-Specific

Por Treviño, Lindsey S., Bingman, William E., Edwards, Dean P., Weigel, NL
Publicado em 2013

Cyclin-Dependent Kinase Activity Is Required for Progesterone Receptor Function: Novel Role for Cyclin A/Cdk2 as a Progesterone Receptor Coactivator

Por Narayanan, Ramesh, Adigun, Abayomi A., Edwards, Dean P., Weigel, Nancy L.
Publicado em 2005

Partial Agonist Activity of the Progesterone Receptor Antagonist RU486 Mediated by an Amino-Terminal Domain Coactivator and Phosphorylation of Serine(400)

Por Wardell, Suzanne E., Narayanan, Ramesh, Weigel, Nancy L., Edwards, Dean P.
Publicado em 2010

Jun Dimerization Protein 2 Functions as a Progesterone Receptor N-Terminal Domain Coactivator

Por Wardell, Suzanne E., Boonyaratanakornkit, Viroj, Adelman, James S., Aronheim, Ami, Edwards, Dean P.
Publicado em 2002

Mechanism of high-mobility group protein B enhancement of progesterone receptor sequence-specific DNA binding

Por Roemer, Sarah C., Adelman, James, Churchill, Mair E. A., Edwards, Dean P.
Publicado em 2008

The Opposing Transcriptional Activities of the Two Isoforms of the Human Progesterone Receptor Are Due to Differential Cofactor Binding

Por Giangrande, Paloma H., A. Kimbrel, Erin, Edwards, Dean P., McDonnell, Donald P.
Publicado em 2000

Regulation of the Amino-Terminal Transcription Activation Domain of Progesterone Receptor by a Cofactor-Induced Protein Folding Mechanism

Por Wardell, Suzanne E., Kwok, Stanley C., Sherman, Lori, Hodges, Robert S., Edwards, Dean P.
Publicado em 2005

Binding-Folding Induced Regulation of AF1 Transactivation Domain of the Glucocorticoid Receptor by a Cofactor That Binds to Its DNA Binding Domain

Por Garza, Anna S., Khan, Shagufta H., Moure, Carmen M., Edwards, Dean P., Kumar, Raj
Publicado em 2011

Structural and Functional Analysis of Domains of the Progesterone Receptor

Por Hill, Krista K., Roemer, Sarah C., Churchill, Mair E.A., Edwards, Dean P.
Publicado no Mol Cell Endocrinol (2011)

Use of HCA in Subproteome-immunization and Screening of Hybridoma Supernatants to Define Distinct Antibody Binding Patterns

Por Szafran, Adam T., Mancini, Maureen G., Nickerson, Jeffrey A., Edwards, Dean P., Mancini, Michael A.
Publicado no Methods (2015)

Influence of domain interactions on conformational mobility of the progesterone receptor detected by hydrogen/deuterium exchange mass spectrometry

Por Goswami, Devrishi, Callaway, Celetta, Pascal, Bruce D., Kumar, Raj, Edwards, Dean P., Griffin, Patrick R.
Publicado no Structure (2014)

Progestin Stimulation of Manganese Superoxide Dismutase and Invasive Properties in T47D Human Breast Cancer Cells

Por Holley, Aaron K., Kiningham, Kelley K., Spitz, Douglas R., Edwards, Dean P., Jenkins, Jeffrey T., Moore, Michael R.
Publicado em 2009

A Progesterone Receptor Co-activator (JDP2) Mediates Activity through Interaction with Residues in the Carboxyl-terminal Extension of the DNA Binding Domain

Por Hill, Krista K., Roemer, Sarah C., Jones, David N. M., Churchill, Mair E. A., Edwards, Dean P.
Publicado em 2009

Lactogenic Hormonal Induction of Long Distance Interactions between β-Casein Gene Regulatory Elements

Por Kabotyanski, Elena B., Rijnkels, Monique, Freeman-Zadrowski, Courtneay, Buser, Adam C., Edwards, Dean P., Rosen, Jeffrey M.
Publicado em 2009

Differential Regulation of Progesterone Receptor-Mediated Transcription by CDK2 and DNA-PK

Por Treviño, Lindsey S., Bolt, Michael J., Grimm, Sandra L., Edwards, Dean P., Mancini, Michael A., Weigel, Nancy L.
Publicado no Mol Endocrinol (2016)