Cyclin-Dependent Kinase Activity Is Required for Progesterone Receptor Function: Novel Role for Cyclin A/Cdk2 as a Progesterone Receptor Coactivator

Our studies examining the role of the cell cycle-regulated kinase cyclin A/Cdk2 in progesterone receptor (PR) action have demonstrated that cyclin-dependent kinase activity is required for PR function and that cyclin A/Cdk2 functions as a PR coactivator. Although Cdk2 can phosphorylate PR, eliminati...

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Autors principals: Narayanan, Ramesh, Adigun, Abayomi A., Edwards, Dean P., Weigel, Nancy L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC538783/
https://ncbi.nlm.nih.gov/pubmed/15601848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.1.264-277.2005
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