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Minireview: Dynamic Structures of Nuclear Hormone Receptors: New Promises and Challenges
Therapeutic targeting of nuclear receptors (NRs) is presently restricted due to 2 constraints: 1) a limited knowledge of the structural dynamics of intact receptor when complexed to DNA and coregulatory proteins; and 2) the inability to more selectively modulate NR actions at specific organ/gene tar...
में बचाया:
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Endocrine Society
2014
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3896641/ https://ncbi.nlm.nih.gov/pubmed/24284822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1334 |
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