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A bead-based proximity assay for BRD4 ligand discovery
Bromodomain-containing proteins have emerged as desirable targets for anti-neoplastic and anti-inflammatory drug discovery. Toward the development of selective inhibitors of the BET family of bromodomains, we optimized bead-based assays to detect interactions between bromodomains and poly-acetylated...
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| 發表在: | Curr Protoc Chem Biol |
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| Main Authors: | , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725578/ https://ncbi.nlm.nih.gov/pubmed/26629616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470559277.ch150024 |
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