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Development of a fluorescence polarization based assay for histone deacetylase ligand discovery
Histone deacetylases (HDACs) regulate many important physiological processes and the discovery of small molecules that modulate HDAC activity has both academic and clinical relevance. HDAC inhibitors, most notably SAHA, have been pursued as cancer chemotherapeutics but may be useful in treating psyc...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2408937/ https://ncbi.nlm.nih.gov/pubmed/18430569 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.04.007 |
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