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On the Inhibition of Histone Deacetylase 8

Histone deacetylases are key regulators of gene expression and have recently emerged as important therapeutic targets for cancer and a growing number of non-malignant diseases. Many widely studied inhibitors of HDACs such as SAHA are thought to have low selectivity within or between the human HDAC i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Estiu, Guillermina, West, Nathan, Mazitschek, Ralph, Greenberg, Edward, Bradner, James E., Wiest, Olaf
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245874/
https://ncbi.nlm.nih.gov/pubmed/20472442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.03.080
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