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Inhibition of Histone Deacetylases

Lysine acetylation of histones is one of the major epigenetic regulators of chromatin conformation and gene expression. The dynamic nature of histone acetylation is determined by the counterbalancing activity of histone acetyltransferase and histone deacetylase (HDAC) enzymes. Acetylation of histone...

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Autores principales: Huang, Yi, Shaw, Patrick G., Davidson, Nancy E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623540/
https://ncbi.nlm.nih.gov/pubmed/15273406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1385/1-59259-828-5:087
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