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Inhibition of Histone Deacetylases

Lysine acetylation of histones is one of the major epigenetic regulators of chromatin conformation and gene expression. The dynamic nature of histone acetylation is determined by the counterbalancing activity of histone acetyltransferase and histone deacetylase (HDAC) enzymes. Acetylation of histone...

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Bibliographic Details
Main Authors: Huang, Yi, Shaw, Patrick G., Davidson, Nancy E.
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3623540/
https://ncbi.nlm.nih.gov/pubmed/15273406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1385/1-59259-828-5:087
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