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Inhibitors of histone demethylation and histone deacetylation cooperate in regulating gene expression and inhibiting growth in human breast cancer cells

Abnormal activities of histone lysine demethylases (KDMs) and lysine deacetylases (HDACs) are associated with aberrant gene expression in breast cancer development. However, the precise molecular mechanisms underlying the crosstalk between KDMs and HDACs in chromatin remodeling and regulation of gen...

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Autors principals: Huang, Yi, Vasilatos, Shauna N., Boric, Lamia, Shaw, Patrick G., Davidson, Nancy E.
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624096/
https://ncbi.nlm.nih.gov/pubmed/21452019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1480-8
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