Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells

Our previous studies demonstrated that lysine-specific demethylase 1 (LSD1) and histone deacetylases (HDACs) closely interact in controlling growth of breast cancer cells. However, the underlying mechanisms are largely unknown. In this study, we showed that knockdown of LSD1 expression (LSD1-KD) by...

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Detalhes bibliográficos
Main Authors: Vasilatos, Shauna N., Katz, Tiffany A., Oesterreich, Steffi, Wan, Yong, Davidson, Nancy E., Huang, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
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Original Manuscript
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670252/
https://ncbi.nlm.nih.gov/pubmed/23354309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt033
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