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Crosstalk between lysine-specific demethylase 1 (LSD1) and histone deacetylases mediates antineoplastic efficacy of HDAC inhibitors in human breast cancer cells

Our previous studies demonstrated that lysine-specific demethylase 1 (LSD1) and histone deacetylases (HDACs) closely interact in controlling growth of breast cancer cells. However, the underlying mechanisms are largely unknown. In this study, we showed that knockdown of LSD1 expression (LSD1-KD) by...

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書誌詳細
主要な著者: Vasilatos, Shauna N., Katz, Tiffany A., Oesterreich, Steffi, Wan, Yong, Davidson, Nancy E., Huang, Yi
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670252/
https://ncbi.nlm.nih.gov/pubmed/23354309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt033
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