Mechanism of Crosstalk between the LSD1 Demethylase and HDAC1 Deacetylase in the CoREST Complex

The transcriptional corepressor complex CoREST is one of seven histone deacetylase complexes that regulate the genome through controlling chromatin acetylation. The CoREST complex is unique in containing both histone demethylase and deacetylase enzymes, LSD1 and HDAC1, held together by the RCOR1 sca...

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Publicado en:Cell Rep
Autores principales: Song, Yun, Dagil, Lisbeth, Fairall, Louise, Robertson, Naomi, Wu, Mingxuan, Ragan, T.J., Savva, Christos G., Saleh, Almutasem, Morone, Nobuhiro, Kunze, Micha B.A., Jamieson, Andrew G., Cole, Philip A., Hansen, D. Flemming, Schwabe, John W.R.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7043024/
https://ncbi.nlm.nih.gov/pubmed/32101746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.01.091
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