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Extranucleosomal DNA enhances the activity of the LSD1/CoREST histone demethylase complex
The promoter regions of active genes in the eukaryotic genome typically contain nucleosomes post-translationally modified with a trimethyl mark on histone H3 lysine 4 (H3K4), while transcriptional enhancers are marked with monomethylated H3K4. The flavin-dependent monoamine oxidase LSD1 (lysine-spec...
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| Publié dans: | Nucleic Acids Res |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4446439/ https://ncbi.nlm.nih.gov/pubmed/25916846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv388 |
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