Control of neuronal differentiation by sumoylation of BRAF35, a subunit of the LSD1-CoREST histone demethylase complex

The LSD1–CoREST histone demethylase complex is required to repress neuronal genes in nonneuronal tissues. Here we show that sumoylation of Braf35, one of the subunits of the complex, is required to maintain full repression of neuron-specific genes and for occupancy of the LSD1–CoREST complex at its...

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Main Authors: Ceballos-Chávez, María, Rivero, Sabrina, García-Gutiérrez, Pablo, Rodríguez-Paredes, Manuel, García-Domínguez, Mario, Bhattacharya, Shomi, Reyes, José C.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361438/
https://ncbi.nlm.nih.gov/pubmed/22570500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1121522109
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