Chemical Probes for Histone-Modifying Enzymes

Por Cole, Philip A.
Publicado em 2008

Open questions: two challenges in chemical biology - chemical engineering and the science of diet

Por Cole, Philip A
Publicado em 2013

Catalytic Mechanisms and Regulation of Protein Kinases

Por Wang, Zhihong, Cole, Philip A.
Publicado no Methods Enzymol (2014)

Switching immune signals on and off

Por Chu, Nam, Cole, Philip A
Publicado no eLife (2015)

Synthetic Approaches to Protein Phosphorylation

Por Chen, Zan, Cole, Philip A.
Publicado no Curr Opin Chem Biol (2015)

Probing the mechanism of enzymatic phosphoryl transfer with a chemical trick

Por Thompson, Paul R., Cole, Philip A.
Publicado em 2001

LSD1 and The Chemistry of Histone Demethylation

Por Culhane, Jeffrey C., Cole, Philip A.
Publicado em 2007

The Chemical Biology of Protein Phosphorylation

Por Tarrant, Mary Katherine, Cole, Philip A.
Publicado em 2009

Probing the Reaction Coordinate of the p300/CBP Histone Acetyltranferase with Bisubstrate Analogs

Por Karukurichi, Kannan R., Cole, Philip A.
Publicado em 2010

Protein Lysine Acetylation by p300/CBP

Por Dancy, Beverley M., Cole, Philip A.
Publicado no Chem Rev (2015)

Expressed protein ligation: A general method for protein engineering

Por Muir, Tom W., Sondhi, Dolan, Cole, Philip A.
Publicado em 1998

Enhanced interrogation: emerging strategies for cell signaling inhibition

Por Huang, Rong, Martinez-Ferrando, Isabel, Cole, Philip A
Publicado em 2010

Structure and chemistry of the p300/CBP and Rtt109 histone acetyltransferases: Implications for histone acetyltransferase evolution and function

Por Wang, Ling, Tang, Yong, Cole, Philip A, Marmorstein, Ronen
Publicado em 2008

Protein Phosphorylation by Semisynthesis: From Paper to Practice

Por Szewczuk, Lawrence M., Tarrant, Mary Katherine, Cole, Philip A.
Publicado em 2009

Reading and Function of a Histone Code Involved in Targeting Corepressor Complexes for Repression

Por Yoon, Ho-Geun, Choi, Youngsok, Cole, Philip A., Wong, Jiemin
Publicado em 2005

Structure of the p300 Histone Acetyltransferase Bound to Acetyl-Coenzyme A and Its Analogues

Por Maksimoska, Jasna, Segura-Peña, Dario, Cole, Philip A., Marmorstein, Ronen
Publicado em 2014

Mechanism-based inhibition of the melatonin rhythm enzyme: Pharmacologic exploitation of active site functional plasticity

Por Khalil, Ehab M., De Angelis, Jacqueline, Ishii, Makoto, Cole, Philip A.
Publicado em 1999

Altered pharmacology and distinct coactivator usage for estrogen receptor-dependent transcription through activating protein-1

Por Cheung, Edwin, Acevedo, Mari Luz, Cole, Philip A., Kraus, W. Lee
Publicado em 2005

Structural basis for the recognition of c-Src by its inactivator Csk

Por Levinson, Nicholas M., Seeliger, Markus A., Cole, Philip A., Kuriyan, John
Publicado em 2008

Comparative Analysis of Small Molecules and Histone Substrate Analogs as LSD1 Lysine Demethylase Inhibitors

Por Culhane, Jeffrey C., Wang, Dongqing, Yen, Paul M., Cole, Philip A.
Publicado em 2010