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Structural basis for the recognition of c-Src by its inactivator Csk

The catalytic activity of the Src family of tyrosine kinases is suppressed by phosphorylation on a tyrosine residue located near the C-terminus (Tyr 527 in c-Src), which is catalyzed by C-terminal Src Kinase (Csk). Given the promiscuity of most tyrosine kinases, it is remarkable that the C-terminal...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Levinson, Nicholas M., Seeliger, Markus A., Cole, Philip A., Kuriyan, John
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494536/
https://ncbi.nlm.nih.gov/pubmed/18614016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.05.051
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