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Structural basis for the recognition of c-Src by its inactivator Csk
The catalytic activity of the Src family of tyrosine kinases is suppressed by phosphorylation on a tyrosine residue located near the C-terminus (Tyr 527 in c-Src), which is catalyzed by C-terminal Src Kinase (Csk). Given the promiscuity of most tyrosine kinases, it is remarkable that the C-terminal...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2494536/ https://ncbi.nlm.nih.gov/pubmed/18614016 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.05.051 |
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