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Catalytic Mechanisms and Regulation of Protein Kinases

Protein kinases transfer a phosphoryl group from ATP onto target proteins and play a critical role in signal transduction and other cellular processes. Here, we review the kinase kinetic and chemical mechanisms and their application in understanding kinase structure and function. Aberrant kinase act...

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Detalhes bibliográficos
Publicado no:Methods Enzymol
Main Authors: Wang, Zhihong, Cole, Philip A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373616/
https://ncbi.nlm.nih.gov/pubmed/25399640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-397918-6.00001-X
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