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Chemical Probes for Histone-Modifying Enzymes
Central to the epigenetic regulation of chromatin remodeling are the histone-modifying enzymes which catalyze reversible lysine acetylation and methylation. From the early discovery of histone deacetylase inhibitors to the more recent identification of histone demethylase blockers, chemical approach...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908280/ https://ncbi.nlm.nih.gov/pubmed/18800048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.111 |
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