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Chemical Probes for Histone-Modifying Enzymes

Central to the epigenetic regulation of chromatin remodeling are the histone-modifying enzymes which catalyze reversible lysine acetylation and methylation. From the early discovery of histone deacetylase inhibitors to the more recent identification of histone demethylase blockers, chemical approach...

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Détails bibliographiques
Auteur principal: Cole, Philip A.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908280/
https://ncbi.nlm.nih.gov/pubmed/18800048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.111
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