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Chemical Probes for Histone-Modifying Enzymes

Central to the epigenetic regulation of chromatin remodeling are the histone-modifying enzymes which catalyze reversible lysine acetylation and methylation. From the early discovery of histone deacetylase inhibitors to the more recent identification of histone demethylase blockers, chemical approach...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Cole, Philip A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908280/
https://ncbi.nlm.nih.gov/pubmed/18800048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.111
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