A carregar...
Comparative Analysis of Small Molecules and Histone Substrate Analogs as LSD1 Lysine Demethylase Inhibitors
LSD1 is a flavin dependent histone demethylase that oxidatively removes methyl groups from Lys-4 of histone H3. LSD1 belongs to the amine oxidase enzyme superfamily which utilize molecular oxygen to transform amines to imines that are hydrolytically cleaved to formaldehyde. In prior studies, it has...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2843942/ https://ncbi.nlm.nih.gov/pubmed/20148560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909996p |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|