X-ray and cryo-EM structures of monomeric and filamentous actin-like protein MamK reveal changes associated with polymerization

por Löwe, Jan, He, Shaoda, Scheres, Sjors H. W., Savva, Christos G.
Publicado no Proc Natl Acad Sci U S A (2016)

The terminase subunits pUL56 and pUL89 of human cytomegalovirus are DNA-metabolizing proteins with toroidal structure

por Scheffczik, Hanno, Savva, Christos G. W., Holzenburg, Andreas, Kolesnikova, Larissa, Bogner, Elke
Publicado em 2002

Crystal structure of calcium dodecin (Rv0379), from Mycobacterium tuberculosis with a unique calcium-binding site

por Arockiasamy, Arulandu, Aggarwal, Anup, Savva, Christos G, Holzenburg, Andreas, Sacchettini, James C
Publicado em 2011

Solubilization and delivery by GroEL of megadalton complexes of the λ holin

por Deaton, John, Savva, Christos G., Sun, Jingchuan, Holzenburg, Andreas, Berry, Joel, Young, Ry
Publicado em 2004

Structure of the lethal phage pinhole

por Pang, Ting, Savva, Christos G., Fleming, Karen G., Struck, Douglas K., Young, Ry
Publicado em 2009

Micron-scale holes terminate the phage infection cycle

por Dewey, Jill S., Savva, Christos G., White, Rebecca L., Vitha, Stanislav, Holzenburg, Andreas, Young, Ry
Publicado em 2010

Stable micron-scale holes are a general feature of canonical holins

por Savva, Christos G., Dewey, Jill S., Moussa, Samir H., To, Kam H., Holzenburg, Andreas, Young, Ry
Publicado em 2013

Structural characterization of ribosome recruitment and translocation by type IV IRES

por Murray, Jason, Savva, Christos G, Shin, Byung-Sik, Dever, Thomas E, Ramakrishnan, V, Fernández, Israel S
Publicado no eLife (2016)

The topology of chromatin-binding domains in the NuRD deacetylase complex

por Millard, Christopher J, Fairall, Louise, Ragan, Timothy J, Savva, Christos G, Schwabe, John W R
Publicado no Nucleic Acids Res (2020)

Structural Insights into Clostridium perfringens Delta Toxin Pore Formation

por Huyet, Jessica, Naylor, Claire E., Savva, Christos G., Gibert, Maryse, Popoff, Michel R., Basak, Ajit K.
Publicado em 2013

Holin triggering in real time

por White, Rebecca, Chiba, Shinobu, Pang, Ting, Dewey, Jill S., Savva, Christos G., Holzenburg, Andreas, Pogliano, Kit, Young, Ry
Publicado em 2011

The holin of bacteriophage lambda forms rings with large diameter

por Savva, Christos G., Dewey, Jill S., Deaton, John, White, Rebecca L., Struck, Douglas K., Holzenburg, Andreas, Young, Ry
Publicado no Mol Microbiol (2008)

Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein

por Bokori-Brown, Monika, Martin, Thomas G., Naylor, Claire E., Basak, Ajit K., Titball, Richard W., Savva, Christos G.
Publicado no Nat Commun (2016)

Crystal structure of Mycobacterium tuberculosis SecA, a preprotein translocating ATPase

por Sharma, Vivek, Arockiasamy, Arulandu, Ronning, Donald R., Savva, Christos G., Holzenburg, Andreas, Braunstein, Miriam, Jacobs, William R., Sacchettini, James C.
Publicado em 2003

Protection against avian necrotic enteritis after immunisation with NetB genetic or formaldehyde toxoids()

por Fernandes da Costa, Sérgio P., Mot, Dorien, Bokori-Brown, Monika, Savva, Christos G., Basak, Ajit K., Van Immerseel, Filip, Titball, Richard W.
Publicado em 2013

Identification of a Key Residue for Oligomerisation and Pore-Formation of Clostridium perfringens NetB

por Fernandes da Costa, Sérgio P., Savva, Christos G., Bokori-Brown, Monika, Naylor, Claire E., Moss, David S., Basak, Ajit K., Titball, Richard W.
Publicado em 2014

The architecture of the spliceosomal U4/U6.U5 tri-snRNP

por Nguyen, Thi Hoang Duong, Galej, Wojciech P., Bai, Xiao-chen, Savva, Christos G., Newman, Andrew J., Scheres, Sjors H. W., Nagai, Kiyoshi
Publicado no Nature (2015)

Structural Changes Enable Start Codon Recognition by the Eukaryotic Translation Initiation Complex

por Hussain, Tanweer, Llácer, Jose L., Fernández, Israel S., Munoz, Antonio, Martin-Marcos, Pilar, Savva, Christos G., Lorsch, Jon R., Hinnebusch, Alan G., Ramakrishnan, V.
Publicado em 2014

The pore structure of Clostridium perfringens epsilon toxin

por Savva, Christos G., Clark, Alice R., Naylor, Claire E., Popoff, Michel R., Moss, David S., Basak, Ajit K., Titball, Richard W., Bokori-Brown, Monika
Publicado no Nat Commun (2019)

Molecular Architecture and Functional Analysis of NetB, a Pore-forming Toxin from Clostridium perfringens

por Savva, Christos G., Fernandes da Costa, Sérgio P., Bokori-Brown, Monika, Naylor, Claire E., Cole, Ambrose R., Moss, David S., Titball, Richard W., Basak, Ajit K.
Publicado em 2013