A combined kinetic push and thermodynamic pull as driving forces for outer membrane protein sorting and folding in bacteria

por Fleming, Karen G.
Publicado en Philos Trans R Soc Lond B Biol Sci (2015)

Taking deterministic control of membrane protein monomer–dimer measurements

por Fleming, Karen G.
Publicado en J Gen Physiol (2018)

Specificity in transmembrane helix–helix interactions can define a hierarchy of stability for sequence variants

por Fleming, Karen G., Engelman, Donald M.
Publicado 2001

Side-chain hydrophobicity scale derived from transmembrane protein folding into lipid bilayers

por Moon, C. Preston, Fleming, Karen G.
Publicado 2011

The soluble, periplasmic domain of OmpA folds as an independent unit and displays chaperone activity by reducing the self-association propensity of the unfolded OmpA transmembrane...

por Danoff, Emily J., Fleming, Karen G.
Publicado 2011

Using tryptophan fluorescence to measure the stability of membrane proteins folded in liposomes

por Moon, C. Preston, Fleming, Karen G.
Publicado 2011

Membrane Defects Accelerate Outer Membrane β-Barrel Protein Folding

por Danoff, Emily J., Fleming, Karen G.
Publicado en Biochemistry (2014)

Aqueous, Unfolded OmpA Forms Amyloid-Like Fibrils upon Self-Association

por Danoff, Emily J., Fleming, Karen G.
Publicado en PLoS One (2015)

BamA Alone Accelerates Outer Membrane Protein Folding In Vitro through a Catalytic Mechanism

por Plummer, Ashlee M., Fleming, Karen G.
Publicado en Biochemistry (2015)

From Chaperones to the Membrane with a BAM!

por Plummer, Ashlee M., Fleming, Karen G.
Publicado en Trends Biochem Sci (2016)

Influence of Protein Scaffold on Side-Chain Transfer Free Energies

por Marx, Dagen C., Fleming, Karen G.
Publicado en Biophys J (2017)

Novel kinetic intermediates populated along the folding pathway of the transmembrane β-barrel OmpA

por Danoff, Emily J., Fleming, Karen G.
Publicado en Biochemistry (2016)

HullRad: Fast Calculations of Folded and Disordered Protein and Nucleic Acid Hydrodynamic Properties

por Fleming, Patrick J., Fleming, Karen G.
Publicado en Biophys J (2018)

Aromatic side chain water-to-lipid transfer free energies show a depth-dependence across the membrane normal

por McDonald, Sarah K., Fleming, Karen G.
Publicado en J Am Chem Soc (2016)

Negative charge neutralization in the loops and turns of outer membrane phospholipase A impacts folding hysteresis at neutral pH

por McDonald, Sarah K., Fleming, Karen G.
Publicado en Biochemistry (2016)

Association energetics of membrane spanning α-helices

por MacKenzie, Kevin R, Fleming, Karen G
Publicado en Curr Opin Struct Biol (2008)

Overcoming hysteresis to attain reversible equilibrium folding for outer membrane phospholipase A in phospholipid bilayers

por Moon, C. Preston, Kwon, Sarah, Fleming, Karen G.
Publicado 2011

Backbone hydrogen bond energies in membrane proteins are insensitive to large changes in local water concentration

por Lessen, Henry J., Majumdar, Ananya, Fleming, Karen G.
Publicado en J Am Chem Soc (2020)

Skp trimer formation is insensitive to salts in the physiological range

por Sandlin, Clifford W., Zaccai, Nathan R., Fleming, Karen G.
Publicado en Biochemistry (2015)

Changes in apparent free energy of helix-helix dimerization in a biological membrane due to point mutations

por Duong, Mylinh T., Jaszewski, Todd M., Fleming, Karen G., MacKenzie, Kevin R.
Publicado 2007