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Aqueous, Unfolded OmpA Forms Amyloid-Like Fibrils upon Self-Association

Unfolded outer membrane beta-barrel proteins have been shown to self-associate in the absence of lipid bilayers. We previously investigated the formation of high molecular weight species by OmpA, with both the transmembrane domain alone and the full-length protein, and discovered that the oligomeric...

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Publicat a:PLoS One
Autors principals: Danoff, Emily J., Fleming, Karen G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4509890/
https://ncbi.nlm.nih.gov/pubmed/26196893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132301
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