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Changes in apparent free energy of helix-helix dimerization in a biological membrane due to point mutations
We present an implementation of the TOXCAT membrane protein self-association assay that measures the change in apparent free energy of transmembrane helix dimerization caused by point mutations. Quantifying the reporter gene expression from cells carrying wild type and mutant constructs shows that s...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2693063/ https://ncbi.nlm.nih.gov/pubmed/17570394 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.05.026 |
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