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Free Energy Landscapes for Amyloidogenic Tetrapeptides Dimerization

The oligomerization of four peptide sequences, KFFE, KVVE, KLLE, and KAAE is studied using replica-exchange molecular dynamics simulations with an atomically detailed peptide model. Previous experimental studies reported that of these four peptides, only those containing phenylalanine and valine res...

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Bibliografiske detaljer
Main Authors: Baumketner, A., Shea, J.-E.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366655/
https://ncbi.nlm.nih.gov/pubmed/16127168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.059196
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