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Cryo-EM structure of lysenin pore elucidates membrane insertion by an aerolysin family protein

Lysenin from the coelomic fluid of the earthworm Eisenia fetida belongs to the aerolysin family of small β-pore-forming toxins (β-PFTs), some members of which are pathogenic to humans and animals. Despite efforts, a high-resolution structure of a channel for this family of proteins has been elusive...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Bokori-Brown, Monika, Martin, Thomas G., Naylor, Claire E., Basak, Ajit K., Titball, Richard W., Savva, Christos G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4823867/
https://ncbi.nlm.nih.gov/pubmed/27048994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11293
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