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Micron-scale holes terminate the phage infection cycle

Holins are small phage-encoded proteins that accumulate harmlessly in the cytoplasmic membrane during the infection cycle until suddenly, at an allele-specific time, triggering to form lethal lesions, or “holes.” In the phages λ and T4, the holes have been shown to be large enough to allow release o...

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Detalhes bibliográficos
Main Authors: Dewey, Jill S., Savva, Christos G., White, Rebecca L., Vitha, Stanislav, Holzenburg, Andreas, Young, Ry
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836697/
https://ncbi.nlm.nih.gov/pubmed/20080651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0914030107
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