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Holin triggering in real time

During λ infections, the holin S105 accumulates harmlessly in the membrane until, at an allele-specific time, suddenly triggering to form irregular holes of unprecedented size (>300 nm), releasing the endolysin from the cytoplasm, resulting in lysis within seconds. Here we used a functional S105–...

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Detalles Bibliográficos
Main Authors: White, Rebecca, Chiba, Shinobu, Pang, Ting, Dewey, Jill S., Savva, Christos G., Holzenburg, Andreas, Pogliano, Kit, Young, Ry
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021014/
https://ncbi.nlm.nih.gov/pubmed/21187415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1011921108
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