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Structural characterization of ribosome recruitment and translocation by type IV IRES

Viral mRNA sequences with a type IV IRES are able to initiate translation without any host initiation factors. Initial recruitment of the small ribosomal subunit as well as two translocation steps before the first peptidyl transfer are essential for the initiation of translation by these mRNAs. Usin...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Murray, Jason, Savva, Christos G, Shin, Byung-Sik, Dever, Thomas E, Ramakrishnan, V, Fernández, Israel S
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861600/
https://ncbi.nlm.nih.gov/pubmed/27159451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13567
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