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Initiation of Translation by Cricket Paralysis Virus IRES Requires Its Translocation in the Ribosome

The cricket paralysis virus internal ribosome entry site (CrPV-IRES) is a folded structure in a viral mRNA that allows initiation of translation in the absence of any host initiation factors. By using recent advances in single-particle electron cryomicroscopy, we have solved the structure of CrPV-IR...

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Detalhes bibliográficos
Main Authors: Fernández, Israel S., Bai, Xiao-Chen, Murshudov, Garib, Scheres, Sjors H.W., Ramakrishnan, V.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4017093/
https://ncbi.nlm.nih.gov/pubmed/24792965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.04.015
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