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Molecular architecture of a eukaryotic translational initiation complex

The last step in eukaryotic translational initiation involves the joining of the large and small subunit of the ribosome, with initiator tRNA (Met-tRNA(i)(Met)) positioned over the start codon of mRNA in the P site. This step is catalyzed by initiation factor eIF5B. We have used recent advances in e...

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Detalles Bibliográficos
Main Authors: Fernández, Israel S., Bai, Xiao-Chen, Hussain, Tanweer, Kelley, Ann C., Lorsch, Jon R., Ramakrishnan, V., Scheres, Sjors H.W.
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836175/
https://ncbi.nlm.nih.gov/pubmed/24200810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1240585
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