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The Mechanism of Eukaryotic Translation Initiation: New Insights and Challenges

Translation initiation in eukaryotes is a highly regulated and complex stage of gene expression. It requires the action of at least 12 initiation factors, many of which are known to be the targets of regulatory pathways. Here we review our current understanding of the molecular mechanics of eukaryot...

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Библиографические подробности
Главные авторы: Hinnebusch, Alan G., Lorsch, Jon R.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3475172/
https://ncbi.nlm.nih.gov/pubmed/22815232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a011544
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