eIF1 controls multiple steps in start codon recognition during eukaryotic translation initiation

Eukaryotic translation initiation factor (eIF) 1 is a central mediator of start codon recognition. Dissociation of eIF1 from the pre-initiation complex allows release of phosphate from the G-protein factor eIF2, triggering downstream events in initiation. Mutations that weaken binding of eIF1 to the...

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Autores principales: Nanda, Jagpreet S., Cheung, Yuen-Nei, Takacs, Julie E., Martin-Marcos, Pilar, Saini, Adesh K., Hinnebusch, Alan G., Lorsch, Jon R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783965/
https://ncbi.nlm.nih.gov/pubmed/19751744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.09.017
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