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Identification of compounds that decrease the fidelity of start codon recognition by the eukaryotic translational machinery
Translation initiation in eukaryotes involves more than a dozen protein factors. Alterations in six factors have been found to reduce the fidelity of start codon recognition by the ribosomal preinitiation complex in yeast, a phenotype referred to as Sui(−). No small molecules are known that affect t...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3039144/ https://ncbi.nlm.nih.gov/pubmed/21220547 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2475211 |
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