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Kinetic analysis of late steps of eukaryotic translation initiation

Little is known about the molecular mechanics of the late events of translation initiation in eukaryotes. We present a kinetic dissection of the transition from a pre-initiation complex (PIC) after start codon recognition to the final 80S initiation complex (IC). The resulting framework reveals that...

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Bibliographic Details
Main Authors: Acker, Michael G., Shin, Byung-Sik, Nanda, Jagpreet S., Saini, Adesh K., Dever, Thomas E., Lorsch, Jon R.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2654283/
https://ncbi.nlm.nih.gov/pubmed/18976658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.10.029
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