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Initiation factor eIF5B catalyzes second GTP-dependent step in eukaryotic translation initiation
Initiation factors IF2 in bacteria and eIF2 in eukaryotes are GTPases that bind Met-tRNA [Formula: see text] to the small ribosomal subunit. eIF5B, the eukaryotic ortholog of IF2, is a GTPase that promotes ribosomal subunit joining. Here we show that eIF5B GTPase activity is required for protein syn...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139205/ https://ncbi.nlm.nih.gov/pubmed/12471154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.262569399 |
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