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Increased expression of eukaryotic translation initiation factors eIF-4E and eIF-2 alpha in response to growth induction by c-myc.

Although activation of c-myc is a critical step in the development of lymphomas and other tumors, its normal function(s) in cell growth remain obscure because few myc-regulated genes are known. myc expression normally increases in response to mitogens and peaks in G1 when additional protein synthesi...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Rosenwald, I B, Rhoads, D B, Callanan, L D, Isselbacher, K J, Schmidt, E V
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46890/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327497/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.6175
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