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Direct eIF2–eIF3 contact in the multifactor complex is important for translation initiation in vivo

Translation initiation factor 3 (eIF3) of Saccharo myces cerevisiae forms a multifactor complex (MFC) with eIFs 1, 2, 5 and Met-tRNA(i)(Met). We previously constructed a subunit interaction model for the MFC. Here we incorporated affinity tags into the three largest eIF3 subunits (eIF3a/TIF32, eIF3b...

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Bibliografske podrobnosti
Main Authors: Valášek, Leoš, Nielsen, Klaus H., Hinnebusch, Alan G.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC131060/
https://ncbi.nlm.nih.gov/pubmed/12411506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf563
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