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Direct eIF2–eIF3 contact in the multifactor complex is important for translation initiation in vivo

Translation initiation factor 3 (eIF3) of Saccharo myces cerevisiae forms a multifactor complex (MFC) with eIFs 1, 2, 5 and Met-tRNA(i)(Met). We previously constructed a subunit interaction model for the MFC. Here we incorporated affinity tags into the three largest eIF3 subunits (eIF3a/TIF32, eIF3b...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
I whakaputaina i:EMBO J
Ngā kaituhi matua: Valášek, Leoš, Nielsen, Klaus H., Hinnebusch, Alan G.
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Publishing Group 2002
Ngā marau:
Urunga tuihono:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC131060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12411506/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf563
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