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Structural Basis for Ribosome Recruitment and Manipulation by a Viral IRES RNA
Canonical cap-dependent translation initiation requires a large number of protein factors that act in a stepwise assembly process. In contrast, internal ribosomal entry sites (IRESs) are cis-acting RNAs that in some cases completely supplant these factors by recruiting and activating the ribosome us...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2669756/ https://ncbi.nlm.nih.gov/pubmed/17124290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1133281 |
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