The Prostate Cancer TMPRSS2:ERG Fusion Synergizes With the Vitamin D Receptor (VDR) to Induce CYP24A1 Expression-Limiting VDR Signaling

A number of preclinical studies have shown that the activation of the vitamin D receptor (VDR) reduces prostate cancer (PCa) cell and tumor growth. The majority of human PCas express a transmembrane protease serine 2 (TMPRSS2):erythroblast transformation-specific (ETS) fusion gene, but most preclini...

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Foilsithe in:Endocrinology
Main Authors: Kim, Jung-Sun, Roberts, Justin M., Bingman, William E., Shao, Longjiang, Wang, Jianghua, Ittmann, Michael M., Weigel, Nancy L.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Endocrine Society 2014
Ábhair:
Cancer-Oncogenes
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377584/
https://ncbi.nlm.nih.gov/pubmed/24926821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2013-2019
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