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Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN

Prostate cancer is the most common visceral malignancy and the second leading cause of cancer deaths in US men. Correlative studies in human prostate cancers reveal a frequent association of the TMPRSS2/ERG (TE) fusion gene with loss of PTEN and studies in mouse models reveal that ERG expression and...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Shao, Longjiang, Wang, Jianghua, Karatas, Omer Faruk, Feng, Shu, Zhang, Yiqun, Creighton, Chad J., Ittmann, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865682/
https://ncbi.nlm.nih.gov/pubmed/29581856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24470
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