Fibroblast growth factor receptor signaling plays a key role in transformation induced by the TMPRSS2/ERG fusion gene and decreased PTEN

Prostate cancer is the most common visceral malignancy and the second leading cause of cancer deaths in US men. Correlative studies in human prostate cancers reveal a frequent association of the TMPRSS2/ERG (TE) fusion gene with loss of PTEN and studies in mouse models reveal that ERG expression and...

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Vydáno v:Oncotarget
Hlavní autoři: Shao, Longjiang, Wang, Jianghua, Karatas, Omer Faruk, Feng, Shu, Zhang, Yiqun, Creighton, Chad J., Ittmann, Michael
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5865682/
https://ncbi.nlm.nih.gov/pubmed/29581856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24470
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