Molecular Basis of Histone Tail Recognition by Human TIP5 PHD Finger and Bromodomain of the Chromatin Remodeling Complex NoRC

Por Tallant, Cynthia, Valentini, Erica, Fedorov, Oleg, Overvoorde, Lois, Ferguson, Fleur M., Filippakopoulos, Panagis, Svergun, Dmitri I., Knapp, Stefan, Ciulli, Alessio
Publicado no Structure (2015)

Discovery of a Series of 5,11-Dihydro-6H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6-ones as Selective PI3K-δ/γ Inhibitors

Por Ferguson, Fleur M., Ni, Jing, Zhang, Tinghu, Tesar, Bethany, Sim, Taebo, Kim, Nam Doo, Deng, Xianming, Brown, Jennifer R., Zhao, Jean J., Gray, Nathanael S.
Publicado no ACS Med Chem Lett (2016)

Binding Hotspots of BAZ2B Bromodomain: Histone Interaction Revealed by Solution NMR Driven Docking

Por Ferguson, Fleur M., Dias, David M., Rodrigues, João P. G. L. M., Wienk, Hans, Boelens, Rolf, Bonvin, Alexandre M. J. J., Abell, Chris, Ciulli, Alessio
Publicado no Biochemistry (2014)

Targeting Low-Druggability Bromodomains: Fragment Based Screening and Inhibitor Design against the BAZ2B Bromodomain

Por Ferguson, Fleur M., Fedorov, Oleg, Chaikuad, Apirat, Philpott, Martin, Muniz, Joao R. C., Felletar, Ildiko, von Delft, Frank, Heightman, Tom, Knapp, Stefan, Abell, Chris, Ciulli, Alessio
Publicado em 2013

A bump-and-hole approach to engineer controlled selectivity of BET bromodomain chemical probes

Por Baud, Matthias G. J., Lin-Shiao, Enrique, Cardote, Teresa, Tallant, Cynthia, Pschibul, Annica, Chan, Kwok-Ho, Zengerle, Michael, Garcia, Jordi R., Kwan, Terence T.-L., Ferguson, Fleur M., Ciulli, Alessio
Publicado no Science (2014)