Differential regulation of metabolic pathways by androgen receptor (AR) and its constitutively active splice variant, AR-V7, in prostate cancer cells

Metastatic prostate cancer (PCa) is primarily an androgen-dependent disease, which is treated with androgen deprivation therapy (ADT). Tumors usually develop resistance (castration-resistant PCa [CRPC]), but remain androgen receptor (AR) dependent. Numerous mechanisms for AR-dependent resistance hav...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Shafi, Ayesha A., Putluri, Vasanta, Arnold, James M., Tsouko, Efrosini, Maity, Suman, Roberts, Justin M., Coarfa, Cristian, Frigo, Daniel E., Putluri, Nagireddy, Sreekumar, Arun, Weigel, Nancy L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2015
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4741655/
https://ncbi.nlm.nih.gov/pubmed/26378018
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