Isoform-specific Activities of Androgen Receptor and its Splice Variants in Prostate Cancer Cells

Androgen receptor (AR) signaling continues to drive castration-resistant prostate cancer (CRPC) in spite of androgen deprivation therapy (ADT). Constitutively active shorter variants of AR, lacking the ligand binding domain, are frequently expressed in CRPC and have emerged as a potential mechanism...

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Détails bibliographiques
Publié dans:Endocrinology
Auteurs principaux: Nagandla, Harika, Robertson, Matthew J, Putluri, Vasanta, Putluri, Nagireddy, Coarfa, Cristian, Weigel, Nancy L
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2020
Sujets:
Research Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253248/
https://ncbi.nlm.nih.gov/pubmed/33300995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa227
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