Isoform-specific Activities of Androgen Receptor and its Splice Variants in Prostate Cancer Cells

Androgen receptor (AR) signaling continues to drive castration-resistant prostate cancer (CRPC) in spite of androgen deprivation therapy (ADT). Constitutively active shorter variants of AR, lacking the ligand binding domain, are frequently expressed in CRPC and have emerged as a potential mechanism...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Endocrinology
Main Authors: Nagandla, Harika, Robertson, Matthew J, Putluri, Vasanta, Putluri, Nagireddy, Coarfa, Cristian, Weigel, Nancy L
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253248/
https://ncbi.nlm.nih.gov/pubmed/33300995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa227
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