Isoform-specific Activities of Androgen Receptor and its Splice Variants in Prostate Cancer Cells

Androgen receptor (AR) signaling continues to drive castration-resistant prostate cancer (CRPC) in spite of androgen deprivation therapy (ADT). Constitutively active shorter variants of AR, lacking the ligand binding domain, are frequently expressed in CRPC and have emerged as a potential mechanism...

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Veröffentlicht in:Endocrinology
Hauptverfasser: Nagandla, Harika, Robertson, Matthew J, Putluri, Vasanta, Putluri, Nagireddy, Coarfa, Cristian, Weigel, Nancy L
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8253248/
https://ncbi.nlm.nih.gov/pubmed/33300995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/endocr/bqaa227
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