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Androgen receptor and its splice variant, AR-V7, differentially induce mRNA splicing in prostate cancer cells
Prostate cancer (PCa) is dependent on the androgen receptor (AR). Advanced PCa is treated with an androgen deprivation therapy-based regimen; tumors develop resistance, although they typically remain AR-dependent. Expression of constitutively active AR variants lacking the ligand-binding domain incl...
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| 發表在: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2021
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7809134/ https://ncbi.nlm.nih.gov/pubmed/33446905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81164-0 |
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